IMPORTANT
INFORMATION
Pronounced: FLEX-eh-rill Generic name: Cyclobenzaprine
hydrochloride
WHAT
IT IS
Flexeril is a muscle relaxant usually recommended
to relieve muscle spasms resulting from injuries such
as sprains, strains, or pulls. Combined with rest
and physical therapy, Flexeril is excellent in relieving
muscular stiffness and pain.
HOW
TO USE THIS MEDICATION
Flexeril may be taken with or without food. It should
be used only for short periods of time, no more than
3 weeks maximum. Since the type of injury that Flexeril
treats will generally improve in a few weeks, there
is no reason to continue its use for a longer period.
For some people, Flexeril may cause dry mouth. Dissolving
a lozenge or candy, chewing gum, or melting ice chips
in your mouth can provide temporary relief.
PRECAUTIONS
The effects of Flexeril during pregnancy have not
been adequately studied. If you are pregnant or plan
to become pregnant, consult with your doctor. It is
not known if Flexeril will appear in breast milk.
However, cyclobenzaprine is related to tricyclic antidepressants,
and some of those drugs tend to appear in breast milk.
If this medication is essential to your health, your
doctor may recommend that you discontinue breastfeeding
your baby until your treatment has been completed.
SIDE
EFFECTS
Side effects generally cannot be anticipated with
Flexeril. If any side effects develop or alter in
intensity, tell your doctor as soon as possible. Only
your doctor can determine if it is safe for you to
continue taking Flexeril. More common side effects
may include: Dizziness, drowsiness, dry mouth Less
common or rare side effects may include:
Abnormal
heartbeats, abnormal sensations, abnormal thoughts
or dreams, aggressive behavior, agitation, anxiety,
bloated feeling, blurred vision, confusion, constipation,
convulsions, decreased appetite, depressed mood, diarrhea,
difficulty falling or staying asleep, difficulty speaking,
disorientation, double vision, excitement, fainting,
fatigue, fluid retention, gas, hallucinations, headache,
heartburn, hepatitis, hives, increased heart rate,
indigestion, inflammation of the stomach, itching,
lack of coordination, liver diseases, loss of sense
of taste, low blood pressure, muscle twitching, nausea,
nervousness, palpitations, paranoia, rash, ringing
in the ears, severe allergic reaction, stomach and
intestinal pain, sweating, swelling of the tongue
or face, thirst, tingling in hands or feet, tremors,
unpleasant taste in the mouth, urinating more or less
than usual, vague feeling of bodily discomfort, vertigo,
vomiting, weakness, yellow eyes and skin. Problems
such as confusion or hallucinations are more likely
in older adults.
DRUG
INTERACTIONS
Serious and potentially fatal reactions may occur
if you take Flexeril with an antidepressant drug known
as an MAO inhibitor (such as Nardil, Parnate) or if
it has been less than 2 weeks since you last took
an MAO inhibitor. You should strictly follow your
doctor's advice regarding the discontinuation of MAO
inhibitors before taking Flexeril. Avoid alcoholic
beverages while taking Flexeril. If Flexeril is taken
with certain other drugs, the effects of either could
be amplified, decreased, or altered. It is especially
important to check with your doctor before combining
Flexeril with the following: Barbiturates such as
phenobarbital Guanethidine and other high blood pressure
drugs Other drugs that slow the central nervous system,
such as Halcion and Xanax Tramadol (Ultram)
NOTES
Flexeril is not a substitute for the physical therapy,
rest, or exercise that your doctor orders for proper
healing. Although Flexeril relieves the pain of strains
and sprains, it is not useful for other types of pain
and should not be used to combat such pain.
DOSEAGE
ADULTS The usual dose is 10 milligrams 3 times a day.
You should not take more than 60 milligrams a day.
MISSED
DOSE
Take it as soon as you remember, if it is within an
hour or so of your scheduled time. If you do not remember
until later, skip the missed dose completely and go
back to your regular schedule. Do not take 2 doses
at one time.
IF
YOU TAKE TOO MUCH
Any medication taken in excess can have serious consequences.
If you suspect a Flexeril overdose, seek medical attention
immediately. Symptoms of Flexeril overdose may include:
Agitation, coma, confusion, congestive heart failure,
convulsions, dilated pupils, disturbed concentration,
drowsiness, hallucinations, high or low temperature,
increased heartbeats, irregular heart rhythms, muscle
stiffness, overactive reflexes, severe low blood pressure,
stupor, and vomiting. High doses also may cause any
of the conditions listed in "Side Effects."
STORAGE
Store away from heat, light, and moisture.